Jennifer Fiegel, Ph.D. (Associate Member)
Assistant Professor, Division of Pharmaceutics, College of Medicine, The University of Iowa
Assistant Professor, Department of Chemical and Biochemical Engineering, College of Engineering, The University of Iowa

http://myweb.uiowa.edu/jfiegel/

Research Interest    

Research in Dr. Jennifer Fiegel''s laboratory focuses on the development of novel drug delivery systems for diseases of the lung, with special emphasis on infectious diseases. Through experimental studies and mathematical modeling, the laboratory designs medical aerosols with an improved ability to target the delivery of therapeutics within the lungs and explores the complex physical interactions between these delivery systems and various cells and fluids native to the lungs. The group is also investigating new ways to suppress the transmission of airborne pathogens via local variations in the lung lining fluid.

Selected Publications:

W. Watanabe, M. Thomas, R. Clarke, A. Klibanov, R. Langer, G. Fuller, J. Fiegel, D. Edwards. Why inhaling salt water changes what we exhale. J. Colloid Interface Sci. 2007; 307(1): 71-78.

J. Fiegel, R. Clarke, D. Edwards. Airborne infectious disease and the suppression of exhaled aerosols [review]. Drug Discovery Today. 2006; 11(1-2):51-57.

D.A. Edwards, J. Fiegel, W. DeHaan, M. Brande, J. Man, R. Clarke. Novel inhalants for control and protection against airborne infections [review]. Respiratory Drug Delivery 2006; 1: 41-48.

J. Fiegel, F. Jin, J. Hanes, K. Stebe. Wetting of a particle in a thin film. J. Colloid Interface Sci. 2005; 291(2):507-514.

J. Fiegel, J. Fu, J. Hanes. Poly(ether-anhydride) microparticle aerosolization improved by controlling particle surface properties. J. Control. Release. 2004; 96(3):411-423.

J. Fiegel, C. Ehrhardt, U.F. Schaefer, C.-M. Lehr, J. Hanes. Large porous particle impingement on lung epithelial cell monolayers: Toward improved particle characterization in the lung. Pharm. Res. 2003; 20(5):788-796.

J. Fu, J. Fiegel, E. Krauland, J. Hanes. New polymer carriers for pulmonary drug delivery. Biomaterials 2002; 23(22):4425-4433.

C. Ehrhardt, J. Fiegel, S. Fuchs, R. Abu-Dahab, U.F. Schaefer, J. Hanes, C.-M. Lehr. Drug absorption by the respiratory mucosa ? Cell culture models and particulate drug carriers. J. Aerosol Med. 2002; 15(2):131-139.

Publications from PubMed