David Meyerholz, D.V.M, Ph.D. (Full Member)
Assist. Professor, Dept. of Pathology, University of Iowa

http://www.medicine.uiowa.edu/Pathology/site/faculty/meyerholz/meyerholz.html

Research Interest    

Dr. Meyerholz is a veterinary pathologist whose research interests focus on pulmonary function, immunity and disease. His research involves the examination, detection and interpretation of cellular changes associated with pulmonary diseases including cystic fibrosis, RSV infection, influenza infection, and SARS-CoV infection. Dr. Meyerholz's laboratory specializes in anatomic phenotyping of new CF models (e.g. pig, ferret) and in developing novel morphologic techniques for the detection of cellular markers and lesions in the lung. Dr. Meyerholz also directs the Comparative Pathology Laboratory (CPL), which provides UI Investigators with scientific support in pathology techniques including necropsy, gross and microscopic examination/interpretation, comprehensive anatomic phenotyping, and histology, as well as consultation on pathology-related aspects of their work.

Selected Publications:

Castilow, EM, Meyerholz DK, Varga SM. IL-13 is required for eosinophil entry into the lung during respiratory syncytial virus vaccine-enhanced disease. Journal of Immunology, 180:2376-2384, 2008.

George CL, Goss KL, Meyerholz DK, Lamb FS, Snyder JM. Surfactant associated protein-A provides critical immunoprotection in neonatal mice. Infection and Immunity, 76:380-390, 2008.

Meyerholz DK, Gallup JM, Lazic T, de Macedo MMA, Lehmkuhl HD, Ackermann MR. Pretreatment with recombinant human vascular endothelial growth factor reduces virus replication and inflammation in a perinatal lamb model of RSV infection. Viral Immunology, 20:188-196, 2007.

McCray PB Jr, Pewe L, Wohlford-Lenane C, Hickey M, Manzel L, Shi L, Netland J, Jia HP, Halabi C, Sigmund CD, Meyerholz DK, Kirby P, Look DC, Perlman S. Lethal infection in K18-hACE2 mice infected with SARS-CoV. Journal of Virology, 81:813-821, 2007.

Publications from PubMed